By using this site, you agree to the Privacy Policy and Terms of Use.
Accept

Amed Post

Breaking News,magazine, sport, life

Notification Show More
Font ResizerAa
Reading: March Madness 2026 odds, picks, best bet for Friday’s Round of 64
Share
Font ResizerAa

Amed Post

Breaking News,magazine, sport, life

Search
Have an existing account? Sign In
Follow US

March Madness 2026 odds, picks, best bet for Friday’s Round of 64

amedpost
Last updated: March 20, 2026 2:44 pm
amedpost
Published: March 20, 2026
Share
SHARE


Contents
  • Iowa State vs. Tennessee State odds, prediction
  • Betting on College Basketball?
  • Why Trust New York Post Betting
Gambling content 21+. The New York Post may receive an affiliate commission if you sign up through our links. Read our editorial standards for more information.

Iowa State is one of the best teams in the country, but the Cyclones seem to be flying under the radar a little bit as we hit the Big Dance.

If not for a last-second loss to Arizona in the Big 12 semifinals, T. J. Otzelberger’s team could have been a No. 1 seed in this field.

Alas, the boys from Ames will need to settle for a No. 2 seed in the Midwest Region.

Iowa State vs. Tennessee State odds, prediction

The Cyclones will open the tournament as a massive favorite against No. 15-seed Tennessee State.

FanDuel has Iowa State laying 24.5 points, with the juice suggesting this number could rise before tip-off Friday.

When you’re handicapping the mismatches in the NCAA Tournament, you’re looking at what skillset the underdog brings to the table and if those strengths can cause a problem for the chalk.


Iowa State head coach T.J. Otzelberger on the sidelines during a college basketball game.
Iowa State head coach T.J. Otzelberger. AP

And while Tennessee State doesn’t have a specific strength that should feasibly threaten Iowa State, it does have one particular feature that could gum up the works a little bit.

The Tigers are a fast-moving bunch, ranking 36th in KenPom’s adjusted tempo metric.

That won’t mean much if Tennessee State can’t score against the fourth-best defense in the country, but it could at least throw a wrench into the system as Iowa State adjusts to the style of play in front of them.

While the Tigers want to go, Iowa State plays at a much slower rate.

KenPom has them at 225th in terms of tempo, and the Cyclones rank 221st in total possessions per game this season.


Betting on College Basketball?


The disparity in styles has every chance of creating a herky-jerky rhythm for this contest, especially in the early going, as these two teams are getting used to one another.

Iowa State likely pulls away and makes this a laugher by the final whistle, but it could look a little nervy in the first half.

The Play: Tennessee State 1H spread (+13.5, bet365)


Why Trust New York Post Betting

Michael Leboff is a long-suffering Islanders fan, but a long-profiting sports bettor with 10 years of experience in the gambling industry. He loves using game theory to help punters win bracket pools, find long shots, and learn how to beat the market in mainstream and niche sports.

‘Challenge’ King Charles and Queen Camilla could face during Italy tour | UK | News
Livvy Dunne opens up on viral F-bomb moment: ‘Really hard’
Keir Starmer dealt huge blow as top spin doctor quits No 10 in latest exit | Politics | News
Drivers told new ‘easy-to-install’ tech could slash costs
Why Samsung’s Galaxy S24 will be beaten this month by something new

Subscribe

Subscribe to our newsletter to get our newest articles instantly!

[mc4wp_form]

Share This Article
Facebook Email Print
Leave a Comment

Leave a Reply Cancel reply

Your email address will not be published. Required fields are marked *

© AMED POST Design Company. All Rights Reserved.
Welcome Back!

Sign in to your account

Username or Email Address
Password

Lost your password?