The Bills will break in their new digs at Highmark Stadium in what is expected to be a shootout with the Lions.
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The Bills had a 36-point outburst in Houston while Detroit just edged the Saints 31-30 in overtime, setting the point total at 54.5.
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What our Post expert thinks about Lions vs. Bills on ‘TNF’
With Detroit missing starting safeties Kerby Joseph and Brian Branch, Dalton Kincaid could be positioned for another big night after his 130-yard opener.
But the bigger question is whether Buffalo can clean up the penalties and defensive lapses quickly enough to avoid turning another winnable game into a late-game sweat.
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Why Trust New York Post Betting
Sean Treppedi handicaps the NFL, NHL, MLB and college football for the New York Post. He primarily focuses on picks that reflect market value while tracking trends to mitigate risk.
