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White Sox vs. Guardians Game 5 prediction: The moneyline pick for the ALDS winner-take-all

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Last updated: October 10, 2026 8:26 pm
amedpost
Published: October 10, 2026
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Contents
    • Learn all you need to know about MLB Betting
  • Why Trust New York Post Betting
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Time for a little divine intervention.

Word from Vatican City is that Pope Leo XIV will be watching and praying for his beloved White Sox from the Sistine Chapel while eating a Chicago-style deep dish pizza … and maybe having a little red wine.

Game 4 saw 16 pitchers head to the mound, including the ice cream vendor and parking lot attendant.

Maybe not in the decisive ALDS Game 5. Cleveland will send the reliable Gavin Williams to the hill.

Williams was 14-8 during the regular season but lost Game 2 when he surrendered two runs over five frames.

He mopped up for an inning when Game 4 was all but over.

The White Sox’s Sean Burke, 11-7 this year, was brilliant, tossing a one-hitter for 5 ²/₃ innings at the Guards in the Game 2 win.


Chicago White Sox pitcher Sean Burke (59) pitches against the Cleveland Guardians during the third inning in game two of the ALDS for the 2026 MLB Playoffs at Progressive Field.
Chicago White Sox pitcher Sean Burke (59) pitches against the Cleveland Guardians during the third inning in game two of the ALDS for the 2026 MLB Playoffs at Progressive Field. IMAGN IMAGES via Reuters Connect

Last chance, Chisox.

The Pope is behind you and, more importantly, so is Stitches. $50 on the White Sox.


Learn all you need to know about MLB Betting


Down -427 ajpierzynskis as we await the final division series game.

The play: White Sox moneyline (+120, FanDuel Sportsbook)


Why Trust New York Post Betting

The one and only Stitches has been handicapping baseball, daily, for the Post since 2019. Miraculously, he has finished in the black twice. But wait there’s more. He showed his versatility by winning the Post’s NFL Best Bet crown last year.

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