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See who’s favored in highly-anticipated rematch

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Last updated: February 24, 2026 8:00 pm
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Published: February 24, 2026
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Odds on Floyd Mayweather Jr. and Manny Pacquiao’s rematch are out. 

In a sequel between two legendary fighters, Mayweather is the early favorite, with FanDuel Sportsbook pegging him at -176 to win the fight over Pacquiao, who is a +138 underdog as of this writing. 

The two will face off in the ring on September 19 at the Sphere in Las Vegas, with both men pushing 50, more than 11 years after their first boxing match in May 2015.

During that fight, it was Mayweather who came out on top, winning by unanimous decision. 


Floyd Mayweather, Jr. (L) of the U.S. lands a left to the face of Manny Pacquiao of the Philippines in the 11th round during their welterweight WBO, WBC and WBA title fight in Las Vegas, Nevada.
Floyd Mayweather, Jr. (L) of the U.S. lands a left to the face of Manny Pacquiao of the Philippines in the 11th round during their welterweight WBO, WBC and WBA title fight in Las Vegas, Nevada. REUTERS

Mayweather was a heavy 3-to-1 favorite before that fight. 

The pair both recently came out of retirement ahead of their high-profile boxing match in Sin City. 

After retiring in 2021, Pacquiao, who is now 47, returned last July to fight Mario Barrios for the WBC welterweight title, which ended in a surprising majority draw. 

Last Friday, before news of the rematch had emerged, Mayweather, who turned 49 on Tuesday, announced that he is coming out of retirement and returning to boxing after his exhibition bout with Mike Tyson on April 25.

“I still have what it takes to set more records in the sport of boxing,” Mayweather said. “From my upcoming Mike Tyson event to my next professional fight afterwards — no one will generate a bigger gate, have a larger global broadcast audience and generate more money with each event — then my events.”

A Mayweather-Pacquiao rematch has been teased at times in the years since their first fight, although negotiations stalled out until the most recent agreement. 

The fight will be streamed live on Netflix.


Why Trust New York Post Betting

Dylan Svoboda is a versatile writer and analyst across many sports. He’s particularly knowledgeable about the big three — MLB, the NFL and the NBA.

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